The Effects of an Interdependent Group Contingency on Student Writing

National data indicate that many students in the United States are not proficient in writing at grade-level expectations (Persky et al., 2003). However, there is not enough research, resources, or support for school personnel to improve student writing (Graham & Harris, 2003). Previous writing intervention studies involving performance feedback methods have shown positive impacts on student writing fluency, but it may be too time consuming for teachers to use in the classroom (Truckenmiller et al., 2014). Teachers need feasible, evidence-based writing interventions that are easy to implement in their classrooms and that motivate students to improve their writing skills. The present dissertation study examines the effects of a classwide interdependent group contingency writing intervention using randomized criteria on student writing production. Participants included 39 students from three first and second grade classrooms at a rural elementary school. A single-case A-B-A design was used to analyze the impact of the intervention on student total words written, the maintenance of student writing production after the intervention was removed, and social validity among students and teachers. Results indicated that students wrote more with the group contingency intervention in place, but experimental control was not established within classrooms due to time constraints. Percent nonoverlapping data and Hedges’ g effect sizes were calculated and yielded minimal to significant effects of the group contingency on student writing production. Students and teachers responded positively to the intervention, with teachers reporting the ease of implementation. Limitations and applications of these findings are discussed

Качество вод нецентрализованных источников питьевого водоснабжения села Тимирязевское (Томский район)

Объектом исследования являются подземные воды, используемые для нецентрализованного водоснабжения села Тимирязевское. Целью работы является оценка качества воды источников нецентрализованного водоснабжения и возможности ее использования для хозяйственно-питьевого водопользования. В процессе исследования были использованы данные химического и микробиологического анализа проб воды, отобранных из нецентрализованных источников водоснабжения. Выявлено, что подземные воды, в их естественном состоянии, для питьевых целей использоваться не могут, необходима дополнительная очистка.The object of the study are groundwater, Used for non-centralized water supply in the village of Timiryazevskoye. The goal Work is the assessment of the quality of water sources of non-centralized Water supply and the possibility of its use for domestic and drinking Water use. In the process of research, the data of chemical and Microbiological analysis of water samples taken from non-centralized Sources of water supply. It is revealed that groundwater, in their natural. Can not be used for drinking purposes, it is necessary Additional cleaning

Analytical and clinical evaluation of DiaSorin Liaison® Calprotectin fecal assay adapted for serum samples

Background Calprotectin is a calcium-binding protein that can be measured in serum, plasma, and feces. Increased serum and plasma calprotectin concentrations have been found in chronic inflammatory rheumatic disorders. An analytical and clinical evaluation of the DiaSorin Liaison (R) fecal Calprotectin assay using LIAISON (R) XL was performed. Methods The protocol included an analytical and clinical evaluation in which imprecision, the linearity of dilution, differences between serum and plasma samples and method comparison with CalproLab (TM) ELISA kit were assessed. Serum calprotectin concentrations in active (n = 26) and remission (n = 23) rheumatoid arthritis (RA) patients were compared. Results The intra-day and inter-day analytical imprecision CVs ranged from 2.9% to 4.0% and 2.7% to 10.4%, respectively. Correlation between measured and expected values was high (R > 0.99), indicating good linearity. The Wilcoxon signed-rank test showed that serum and plasma matched samples presented statistically significant differences (p < 0.001) being the highest concentrations of calprotectin observed in serum samples. Deming regression equation was as follows: Diasorin calprotectin (mu g/ml) = -0.32 (95% CI: -0.65 - -0.05) +1.58 (95% CI: 1.42-1.79).* Calprolab calprotectin (mu g/ml). Significantly higher serum calprotectin levels were found in RA patients with active disease when compared to patients with low disease activity or in clinical remission (mean +/- SD) [(3.35 mu g/ml +/- 1.55) vs. (1.63 mu g/ml +/- 0.52), p < 0.001] and these levels correlated well with all disease activity indices. Conclusions The DiaSorin Liaison (R) fecal Calprotectin assay adapted for serum samples showed adequate technical performances and the clinical performances were similar to other assays

The living and the dead; an investigation into the status of erasure within the floor of Bath Abbey

The floor of Bath Abbey offers a singular test of authenticity. Nineteenth century repairs and additions caused horizontal grave markers, which comprise the majority of the Abbey’s floor, to become separated from the burial sites they were intended to memorialize. A century and a half of further occupation has had the effect of removing many inscriptions as surfaces are worn smooth. The result is a patchwork of unintended edits and accidental poetry. This paper explores the notions of authenticity, essence, memorial and erasure as they pertain to the Abbey floor, in particular with regard to the role the body plays in inhabiting/eroding the floor—from both above and below. The author argues that the stones which are most out of place or worn to a state of erasure are no less authentic than their intact equivalents, but that they can be considered to have moved to another state of authenticity rich in resonance and meaning. This paper, in short, is a defense of erasure and that erosion through occupation may be considered a form of social memory; indeed, the marks of walking become the inscription. In other words, the undesigned (erasure, the cutting and repositioning of ledger stones, the missing inscriptions) becomes considered not as a form of dirt but as the positive traces of on-going and meaningful occupation

The Regeneration Games: Commodities, Gifts and the Economics of London 2012

This paper considers contradictions between two concurrent and tacit conceptions of the Olympic ‘legacy’, setting out one conception that understands the games and their legacies as gifts alongside and as counterpoint to the prevailing discourse, which conceives Olympic assets as commodities. The paper critically examines press and governmental discussion of legacy, in order to locate these in the context of a wider perspective contrasting ‘gift’ and ‘commodity’ Olympics – setting anthropological conceptions of gift-based sociality as a necessary supplement to contractual and dis-embedded socioeconomic organizational assumptions underpinning the commodity Olympics. Costbenefit planning is central to modern city building and mega-event delivery. The paper considers the insufficiency of this approach as the exclusive paradigm within which to frame and manage a dynamic socio-economic and cultural legacy arising from the 2012 games

Plasma calprotectin as a biomarker of ultrasound synovitis in rheumatoid arthritis patients receiving IL-6 antagonists or JAK inhibitors

To analyse the accuracy of plasma calprotectin in patients with rheumatoid arthritis (RA) receiving monoclonal antibodies against IL-6 receptors (anti-rIL-6) or JAK inhibitors (JAKis) in detecting ultrasound (US) synovitis and compare it with acute phase reactants [high-sensitivity C-reactive protein (hs-CRP) and ESR].An observational cross-sectional study of RA patients receiving anti-rIL-6 (tocilizumab or sarilumab) or JAKi, (baricitinib or tofacitinib) was made. Plasma calprotectin for the diagnosis of US synovitis [synovial hypertrophy grade (SH)???2 plus power Doppler signal (PD)???1] was analysed using receiver operating characteristic curves (ROCs). The performance of ESR and hs-CRP was also studied. The three ROC curves were compared to determine which had the highest discriminatory power. Associations between plasma calprotectin and US scores were made using correlation analysis.Sixty-three RA patients were included. Mean plasma calprotectin levels were significantly higher in patients with US synovitis than in those without (0.89?±?0.85 vs 0.30?±?0.12 ?g/ml; p?=?0.0003). A moderate correlation between calprotectin and all US scores (HS score Rho?=?0.479; PD score Rho?=?0.492; and global score Rho?=?0.495) was found. The discriminatory capacity of plasma calprotectin showed an AUC of 0.795 (95% CI: 0.687-0.904). The AUC of hs-CRP and ESR was 0.721 and 0.564, respectively. hs-CRP serum levels showed a low positive correlation with the three US scores (Rho?<?0.40). After analysis according to the drugs administered, the correlation disappeared in patients receiving anti-rIL-6.Plasma calprotectin may be a sensitive biomarker of synovial inflammation in RA patients treated with anti-rIL-6 or JAKi.© The Author(s), 2022

An Amusing Look at the Host of the Periodic Nuclear Transient ASASSN-14ko Reveals a Second AGN

We present Multi-Unit Spectroscopic Explorer (MUSE) integral-field spectroscopy of ESO 253$-$G003, which hosts a known Active Galactic Nucleus (AGN) and the periodic nuclear transient ASASSN-14ko, observed as part of the All-weather MUse Supernova Integral-field of Nearby Galaxies (AMUSING) survey. The MUSE observations reveal that the inner region hosts two AGN separated by $1.4\pm0.1~\rm{kpc}$ (\approx 1.\!\!^{\prime\prime}7). The brighter nucleus has asymmetric broad, permitted emission-line profiles and is associated with the archival AGN designation. The fainter nucleus does not have a broad emission-line component but exhibits other AGN characteristics, including $v_{\rm{FWHM}}\approx 700~\rm{km}~\rm{s}^{-1}$ forbidden line emission, $\log_{10}(\rm{[OIII]}/\rm{H}\beta) \approx 1.1$, and high excitation potential emission lines such as [Fe$~$VII]$~\lambda6086$ and He$~$II$~\lambda4686$. The host galaxy exhibits a disturbed morphology with large kpc-scale tidal features, potential outflows from both nuclei, and a likely superbubble. A circular relativistic disk model cannot reproduce the asymmetric broad emission-line profiles in the brighter nucleus, but two non-axisymmetric disk models provide good fits to the broad emission-line profiles: an elliptical disk model and a circular disk + spiral arm model. Implications for the periodic nuclear transient ASASSN-14ko are discussed.Comment: 20 pages, 16 figures, and 2 tables. Accepted by MNRA

Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias

INTRODUCTION: Synaptic damage, axonal neurodegeneration, and neuroinflammation are common features in Alzheimer's disease (AD), frontotemporal dementia (FTD), and Creutzfeldt-Jakob disease (CJD). METHODS: Unicentric cohort of 353 participants included healthy control (HC) subjects, AD continuum stages, genetic AD and FTD, and FTD and CJD. We measured cerebrospinal fluid neurofilament light (NF-L), neurogranin (Ng), 14-3-3, and YKL-40 proteins. RESULTS: Biomarkers showed differences in HC subjects versus AD, FTD, and CJD. Disease groups differed between them except AD versus FTD for YKL-40. Only NF-L differed between all stages within the AD continuum. AD and FTD symptomatic mutation carriers presented differences with respect to HC subjects. Applying the AT(N) system, 96% subjects were positive for neurodegeneration if 14-3-3 was used, 94% if NF-L was used, 62% if Ng was used, and 53% if YKL-40 was used. DISCUSSION: Biomarkers of synapse and neurodegeneration differentiate HC subjects from neurodegenerative dementias and between AD, FTD, and CJD. NF-L and 14-3-3 performed similar to total tau when AT(N) system was applied